BDBM22572 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}-N-[(2R)-1-hydroxybutan-2-yl]acetamide::CHEMBL24957::alpha-substituted indomethacin ethanolamide, 8

SMILES CC[C@H](CO)NC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12

InChI Key InChIKey=GKJWXEORYGBJFS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22572   

TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22572(CHEMBL24957 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 5.90E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22572(CHEMBL24957 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Michigan State University

LigandPNGBDBM22572(CHEMBL24957 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibitory concentration against prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Michigan State University

LigandPNGBDBM22572(CHEMBL24957 | 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed