BDBM21687 ({[({[(2R,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::dGTP::deoxyguanosine triphosphate

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1

InChI Key InChIKey=HAAZLUGHYHWQIW-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21687   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM21687(deoxyguanosine triphosphate | ({[({[(2R,3S,5R)-5-(...)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM21687(deoxyguanosine triphosphate | ({[({[(2R,3S,5R)-5-(...)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptase assessed as L-3'-azido-NTP incorporation in nascent DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetDNA polymerase subunit gamma-1(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM21687(deoxyguanosine triphosphate | ({[({[(2R,3S,5R)-5-(...)
Affinity DataKd:  800nMAssay Description:Binding affinity to exonuclase deficient human recombinant DNA polymerase gamma E200A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed