BDBM21624 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid::Thiazolylamino, 12

SMILES Cc1cc(ccc1F)-c1csc(Nc2ccc(C(O)=O)c(O)c2)n1

InChI Key InChIKey=LKZZDHKJFDTYCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21624   

LigandPNGBDBM21624(4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]a...)
Affinity DataIC50: 138nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM21624(4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]a...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed