BDBM190653 PT172

SMILES CCCCCCc1ccn(Cc2ccccc2Cl)c(=O)c1

InChI Key InChIKey=PJBRBZYHOXOPFM-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190653   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Yersinia pestis)
University of Wurzburg

LigandPNGBDBM190653(PT172)
Affinity DataIC50: 5.50E+4nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] [T276S](Yersinia pestis)
University of Wurzburg

LigandPNGBDBM190653(PT172)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values for the inhibition of wildtype and mutant forms of ypFabV were performed by adding varying concentrations of inhibitor dissolved in dimet...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Wuerzburg

LigandPNGBDBM190653(PT172)
Affinity DataKi:  11nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20 °C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed