BDBM181146 US9138393, Adenine::US9144538, Adenine

SMILES Nc1ncnc2[nH]cnc12

InChI Key InChIKey=GFFGJBXGBJISGV-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 181146   

TargetCytochrome P450 3A4(Human)
The Procter & Gamble

US Patent

LigandBDBM181146(US9138393, Adenine | US9144538, Adenine)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
KEGGPC cidPC sidSimilars

In DepthDetails
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TargetCytochrome P450 3A4(Human)
The Procter & Gamble

US Patent

LigandBDBM181146(US9138393, Adenine | US9144538, Adenine)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
KEGGPC cidPC sidSimilars

In DepthDetails
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TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM181146(US9138393, Adenine | US9144538, Adenine)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
KEGGPC cidPC sidSimilars

In DepthDetails Article
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