BDBM17941 (2S,4S,5S)-5-[(2S)-2-[(2S)-2-benzyl-3-[(2-methylpropane-2-)sulfonyl]propanamido]-3-(1H-imidazol-4-yl)propanamido]-N-butyl-6-cyclohexyl-4-hydroxy-2-(propan-2-yl)hexanamide::CGP 38560
SMILES CCCCNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)CS(=O)(=O)C(C)(C)C)C(C)C
InChI Key InChIKey=GGKXIITZBSPCQP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 17941
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 8.20E+3nMpH: 2.0 T: 2°CAssay Description:In vitro potencies of compounds against purified porcine pepsin were determined by its cleavage of substrate hemoglobin. After incubation, proteins w...More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
Affinity DataIC50: 3.27E+4nMAssay Description:Compound was evaluated for the percent inhibition of pepsinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in humanMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Compound was evaluated for the percent inhibition of Cathepsin D in BovineMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of human renin.More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity against aspartic protease renin.More data for this Ligand-Target Pair