BDBM176764 2,5-Di-tert-butylhydroquinone::CAS# 88-58-4::US9688816, 7

SMILES CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C

InChI Key InChIKey=JZODKRWQWUWGCD-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 176764   

TargetEstrogen receptor(Human)
Sabic Global Technologies

US Patent
LigandPNGBDBM176764(US9688816, 7 | 2,5-Di-tert-butylhydroquinone | CAS...)
Affinity DataIC50: 2.50E+5nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor beta(Human)
Sabic Global Technologies

US Patent
LigandPNGBDBM176764(US9688816, 7 | 2,5-Di-tert-butylhydroquinone | CAS...)
Affinity DataIC50: 2.50E+5nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM176764(US9688816, 7 | 2,5-Di-tert-butylhydroquinone | CAS...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rabbit SERCA1b expressed in COS7 cells microsomal membranes preincubated for 10 mins followed by addition of ATP and measured after 40 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 3(Human)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM176764(US9688816, 7 | 2,5-Di-tert-butylhydroquinone | CAS...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human SERCA3a expressed in COS7 cells microsomal membranes preincubated for 10 mins followed by addition of ATP and measured after 40 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 2(Human)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM176764(US9688816, 7 | 2,5-Di-tert-butylhydroquinone | CAS...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human SERCA2b expressed in COS7 cells microsomal membranes preincubated for 10 mins followed by addition of ATP and measured after 40 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed