BDBM17594 A-357300::CHEMBL352764::N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfanyl)pentanoyl]-3-chlorobenzohydrazide::bestatin-type inhibitor, 9

SMILES CC(C)SCC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1

InChI Key InChIKey=BYBVYIPUGPZRSX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 17594   

TargetMethionine aminopeptidase 2(Human)
Abbott Laboratories

LigandPNGBDBM17594(N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfan...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMethionine aminopeptidase 1(Human)
Abbott Laboratories

LigandPNGBDBM17594(N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfan...)
Affinity DataIC50: 5.70E+4nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMethionine aminopeptidase 1(Human)
Abbott Laboratories

LigandPNGBDBM17594(N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfan...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Abbott Laboratories

LigandPNGBDBM17594(N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfan...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human methionine aminopeptidase-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Abbott Laboratories

LigandPNGBDBM17594(N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfan...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human MetAP2 using Met-Ala-Ser as substrate measured at 20 secs interval for 20 mins by AAO/horse radish peroxidase enzyme ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed