BDBM17323 N-{4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl}-N-methylacetamide::cyclohexylalanine derived inhibitor, 25

SMILES C[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)C1CCC(CC1)N(C)C(C)=O

InChI Key InChIKey=BZFQBRSDORUYAB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17323   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM17323(N-{4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM17323(N-{4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1...)
Affinity DataIC50: 2.50E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM17323(N-{4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed