BDBM17135 3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carbamoyl]-6-methoxyphenyl}-4-{[2-(methylamino)-1H-imidazol-1-yl]methyl}thiophene-2-carboxamide::Thiophene-Anthranilamide, 17m::ZK 813039::ZK813039

SMILES CNc1nccn1Cc1csc(C(=O)Nc2c(OC)cc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c1Cl

InChI Key InChIKey=LLHSZBPXQIOQJJ-UHFFFAOYSA-N

Data  6 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 17135   

TargetCoagulation factor X(Human)
Berlex Biosciences

LigandPNGBDBM17135(Thiophene-Anthranilamide, 17m | ZK813039 | 3-chlor...)
Affinity DataKi:  0.00500nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Berlex Biosciences

LigandPNGBDBM17135(Thiophene-Anthranilamide, 17m | ZK813039 | 3-chlor...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Rat)
Berlex Biosciences

LigandPNGBDBM17135(Thiophene-Anthranilamide, 17m | ZK813039 | 3-chlor...)
Affinity DataKi:  0.0600nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Dog)
Berlex Biosciences

LigandPNGBDBM17135(Thiophene-Anthranilamide, 17m | ZK813039 | 3-chlor...)
Affinity DataKi:  0.310nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

LigandPNGBDBM17135(Thiophene-Anthranilamide, 17m | ZK813039 | 3-chlor...)
Affinity DataKi:  990nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
Berlex Biosciences

LigandPNGBDBM17135(Thiophene-Anthranilamide, 17m | ZK813039 | 3-chlor...)
Affinity DataKi: >5.00E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed