BDBM1707 Cyclic Cyanoguanidine deriv. 8w::[4R-(4a,5a,6B,7B)]-[Hexahydro-5,6-dihydroxy-1,3-bis[[4-(hydroxymethoxy)phenyl]methyl]-4,7-bis(phenylmethyl)-2H-1,3-diazepin-2-ylidene]cyanamide::{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({[4-(hydroxymethyl)phenyl]methyl})-1,3-diazepan-2-ylidene]amino}carbonitrile
SMILES [#8]-[#6]-c1ccc(-[#6]-[#7]2-[#6@H](-[#6]-c3ccccc3)-[#6@H](-[#8])-[#6@@H](-[#8])-[#6@@H](-[#6]-c3ccccc3)-[#7](-[#6]-c3ccc(-[#6]-[#8])cc3)\[#6]-2=[#7]\C#N)cc1
InChI Key InChIKey=FYWRFEDYXVLCQU-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1707
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 11nM ΔG°: -11.3kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair