BDBM15238 4-[1-(cyclopropylmethyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyrimidin-2-amine::C14316::SB218655::SB3

SMILES Nc1nccc(n1)-c1c(ncn1CC1CC1)-c1ccc(F)cc1

InChI Key InChIKey=DFEYXQGDDCDXJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15238   

TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15238(SB3 | C14316 | 4-[1-(cyclopropylmethyl)-4-(4-fluor...)
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
University of Texas At Dallas

LigandPNGBDBM15238(SB3 | C14316 | 4-[1-(cyclopropylmethyl)-4-(4-fluor...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15238(SB3 | C14316 | 4-[1-(cyclopropylmethyl)-4-(4-fluor...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human MAPK p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed