BDBM15237 4-[1-(cyclopropylmethyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine::CHEMBL96741::PYRIDINYLIMIDAZOLE::SB2::SB216995

SMILES Fc1ccc(cc1)-c1ncn(CC2CC2)c1-c1ccncc1

InChI Key InChIKey=ROKOFZNQCIIJMI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 15237   

TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
University of Texas At Dallas

LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram seminal vesicleMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of p38-alpha MAPK by non-radioactive immunosorbent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human MAPK p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed