BDBM141899 US8921421, L-257::hDDAH inhibitor, 2a

SMILES COCCNC(=N)NCCC[C@H](N)C(O)=O

InChI Key InChIKey=XMBSMMCPKFDGEO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141899   

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-Universitaet Zu Kiel

US Patent
LigandPNGBDBM141899(hDDAH inhibitor, 2a | US8921421, L-257)
Affinity DataKi:  1.30E+4nM IC50: 2.90E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-Universitaet Zu Kiel

US Patent
LigandPNGBDBM141899(hDDAH inhibitor, 2a | US8921421, L-257)
Affinity DataKi:  1.30E+4nM ΔG°:  -6.93kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed