BDBM13174 (2S,4S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)propanamido]butanoyl]-4-phenoxy-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]pyrrolidine-2-carboxamide::Capped Tripeptide Analog 10::H-N-Me-Ala-Tle-(4S)-4-phenoxy-Pro-(R)-tetrahydronaphth-1-yl Amide

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H]1CCCc2ccccc12)Oc1ccccc1)C(C)(C)C

InChI Key InChIKey=QKPXPZYQPBWDHS-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13174   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Queen'S University of Belfast

Curated by ChEMBL
LigandPNGBDBM13174(H-N-Me-Ala-Tle-(4S)-4-phenoxy-Pro-(R)-tetrahydrona...)
Affinity DataKd:  5nMAssay Description:Binding affinity to XIAP BIR3-domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Abbott Laboratories

LigandPNGBDBM13174(H-N-Me-Ala-Tle-(4S)-4-phenoxy-Pro-(R)-tetrahydrona...)
Affinity DataKd:  5nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed