BDBM11851 3-phenyl-N-{1-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]ethyl}-2-[(2,4,6-trimethylbenzene)sulfonamido]propanamide::5-mercapto-1,3,4-thiadiazole 12q

SMILES CC(NC(=O)C(Cc1ccccc1)NS(=O)(=O)c1c(C)cc(C)cc1C)C(=O)Nc1nnc(S)s1

InChI Key InChIKey=OLEDPIQVUZOZBZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 11851   

TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi Di Firenze

LigandPNGBDBM11851(3-phenyl-N-{1-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)c...)
Affinity DataKi:  1.70E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11851(3-phenyl-N-{1-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)c...)
Affinity DataKi:  2.40E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11851(3-phenyl-N-{1-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)c...)
Affinity DataKi:  2.50E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11851(3-phenyl-N-{1-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)c...)
Affinity DataKi:  2.90E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM11851(3-phenyl-N-{1-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)c...)
Affinity DataKi:  3.30E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate were used for assessing the catalytic activity and inhibition of the MMPs by the spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed