BDBM11593 5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(3,5-dimethoxyphenyl)pyrimidin-4-amine::Aminomethylpyrimidine 1e

SMILES COc1cc(OC)cc(c1)-c1nc(N)c(CN)c(n1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=RCJFINNFYUNFGH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11593   

TargetDipeptidyl peptidase 4(Human)
Graduate University of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM11593(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(3,5-dime...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Graduate University of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM11593(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(3,5-dime...)
Affinity DataIC50: 0.100nMAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Graduate University of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM11593(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(3,5-dime...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of dipeptidyl peptidase 4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article