BDBM11444 5-(3-bromophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine::pyrazolo[1,5-a]pyrimidine 2::pyrazolo[1,5-a]pyrimidine 4

SMILES Brc1cccc(c1)-c1cc(NCc2ccncc2)n2nccc2n1

InChI Key InChIKey=BUXUEPKVOZSCGP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11444   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Vernalis (R&D)

LigandPNGBDBM11444(5-(3-bromophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1...)
Affinity DataIC50: 1.80E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
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TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Vernalis (R&D)

LigandPNGBDBM11444(5-(3-bromophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1...)
Affinity DataIC50: 1.80E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Martin-Luther-University Halle-Wittenberg

LigandPNGBDBM11444(5-(3-bromophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1...)
Affinity DataIC50: 960nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed