BDBM11340 Hydroxamate 21::N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-methylbutanamide

SMILES COc1ccc(cc1)S(=O)(=O)NC(C(C)C)C(=O)NO

InChI Key InChIKey=SUEBJDNLBVTIQP-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11340   

TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi:  33nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi:  38nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi:  39nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi:  82nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi:  103nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi:  126nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi:  126nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11340(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3-meth...)
Affinity DataKi: >200nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed