BDBM11339 Hydroxamate 20::N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzene)sulfonamido]butanamide

SMILES CC(C)C(NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)C(=O)NO

InChI Key InChIKey=VSJBIWYXNLUPIE-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 11339   

TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataIC50: 138nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  8nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  11nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  13nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  40nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  41nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  41nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  89nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  89nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  104nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11339(N-hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorobenzen...)
Affinity DataKi:  139nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed