BDBM11335 2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfonamido]-N-hydroxypropanamide::Hydroxamate 16

SMILES CC(N(Cc1ccccc1)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)NO

InChI Key InChIKey=IWTGCCHOUSDKHV-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 11335   

TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataIC50: 26nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  3.20nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  4.30nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  4.90nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  12nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  26nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  92nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  107nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11335(2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfo...)
Affinity DataKi:  121nM ΔG°:  -9.43kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed