BDBM11334 Hydroxamate 15::N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propanamide

SMILES COc1ccc(cc1)S(=O)(=O)NC(C)C(=O)NO

InChI Key InChIKey=VOESHNWTIDIZCL-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 11334   

Target72 kDa type IV collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataIC50: 87nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  30nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  32nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  35nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  87nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  125nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  130nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  137nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi:  138nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11334(N-hydroxy-2-[(4-methoxybenzene)sulfonamido]propana...)
Affinity DataKi: >200nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed