BDBM11323 4,5,6,7-tetrabromo-1H-1,2,3-benzotriazole::4,5,6,7-tetrabromo-1H-benzotriazole (14)::CHEMBL177820::TBB
SMILES Brc1c(Br)c(Br)c2[nH]nnc2c1Br
InChI Key InChIKey=OMZYUVOATZSGJY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 11323
Affinity DataKd: 7.11E+3nMAssay Description:To assess direct binding of inhibitors to oxidized NQO2 (NQO2ox), fluorescence quenching of FAD was monitored with an excitation wavelength of 350 nm...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of rat liver CK2 phosphorylation using RRRADDSDDDDD as substrate in presence of [32p]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant GST-tagged CK-2 using RRRADDSDDDDD as substrate incubated for 5 mins by scintillation counter analysisMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 790nMAssay Description:Binding affinity to recombinant human CK2alpha/beta expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against hepatitis C virus helicaseMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human CK2alpha using RRRDDDSDDD peptide substrate by P81 filter-binding assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of DYRK1aMore data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+4nMAssay Description:To determine the IC50 value of each inhibitor, reactions were initiated by addition of 154 pM NQO2 to a reaction buffer containing 150 μM SCDP a...More data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:The activity of CK2α was tested using P81 filter isotopic assay, as it was described earlier [Łukowska-Chojnacka et al., Bioorg. Med. Chem....More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of CK2alpha in human PLC1 cells using (Arg)3(Glu)3Thr(Glu)3 as substrate after 24 hrs in presence of [32P]gammaGTPMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Binding affinity to CK2alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 400nM ΔG°: -8.63kcal/mole IC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of rat liver CK2 phosphorylation using RRRADDSDDDDD as substrate in presence of [32p]-ATPMore data for this Ligand-Target Pair