BDBM111586 US8618098, I-1::US8822457, I-1

SMILES CNC(=O)Nc1cc(cn(C)c1=O)-c1cccc(c1C)-n1cnc2cc(ccc2c1=O)C(C)(C)C

InChI Key InChIKey=MCCQXDYJMDEUOT-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 111586   

TargetTyrosine-protein kinase BTK(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM111586(US8822457, I-1 | US8618098, I-1)
Affinity DataIC50: 112nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)