BDBM106697 CHEMBL1957353::US8586620, 43

SMILES CN1CCC(CC1)c1c[nH]c2ccc(cc12)N=C(N)c1cccs1

InChI Key InChIKey=XGAXVNUTGQANPL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 106697   

TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50: 1.88E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50: 3.26E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNitric oxide synthase, inducible(Human)
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50: 5.80E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine 1D receptor(Bovine)
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50: 570nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50: 5.82E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed