BDBM104911 CHEMBL493116::US8569313, Inhibitor 23

SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CC1)C(N)=O

InChI Key InChIKey=MPYRGEWLKUBJJE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 104911   

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  12.1nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSuppressor of tumorigenicity 14 protein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  13nMAssay Description:Inhibition of matriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed