BDBM103961 ATX inhibitor 10::Disubstituted aryl-Me ATX inhibitor 3::Monosubstituted aryl-Me ATX inhibitor 5
SMILES CN1CCN(CC1)C1=NC(=O)\C(S1)=C\c1ccc(Cl)c(Cl)c1
InChI Key InChIKey=BSGZTQWZIBOTMJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 103961
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mouse)
The University of Tokyo
The University of Tokyo
3D Structure (crystal)TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mouse)
The University of Tokyo
The University of Tokyo
Affinity DataIC50: 640nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mouse)
The University of Tokyo
The University of Tokyo
Affinity DataIC50: 240nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant ATXMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of ATX (unknown origin) expressed in human HEK293 cells using TG-mTMP as substrate after 2 hrs by fluorescence based plate reader assayMore data for this Ligand-Target Pair