BDBM103575 ATX inhibitor 10 analogue 5::US8551988, 65

SMILES OB(O)c1cccc(CN2CCN(CC2)C2=NC(=O)\C(S2)=C\c2ccc(Cl)c(Cl)c2)c1

InChI Key InChIKey=ZCKGWOBAJNWRNC-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103575   

LigandPNGBDBM103575(ATX inhibitor 10 analogue 5 | US8551988, 65)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM103575(ATX inhibitor 10 analogue 5 | US8551988, 65)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant ATXMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM103575(ATX inhibitor 10 analogue 5 | US8551988, 65)
Affinity DataIC50: 13nMAssay Description:Inhibition of ATX (unknown origin) expressed in human HEK293 cells using TG-mTMP as substrate after 2 hrs by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)