BDBM10352 1-(4-Methylthiobenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione::1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(pyridin-3-yloxy)methyl]pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione::Pyridine Analogue 21d

SMILES CSc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COc2cccnc2)cc1

InChI Key InChIKey=IZQMNYSMAWSYDA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 10352   

TargetCaspase-3(Human)
Washington University

LigandPNGBDBM10352(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(...)
Affinity DataIC50: 4.40nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM10352(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(...)
Affinity DataIC50: 23.3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-1(Human)
Washington University

LigandPNGBDBM10352(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(...)
Affinity DataIC50: 5.00E+4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM10352(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(...)
Affinity DataIC50: 5.00E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM10352(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(...)
Affinity DataIC50: 5.00E+4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM10352(1-{[4-(methylsulfanyl)phenyl]methyl}-5-{[(2S)-2-[(...)
Affinity DataIC50: 4.37nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed