BDBM100205 MLS000561583::N-[5-[2-(5-chloro-2-methoxy-anilino)thiazol-4-yl]-4-methyl-thiazol-2-yl]-2,2-dimethyl-propionamide::N-[5-[2-(5-chloro-2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide::N-[5-[2-(5-chloro-2-methoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-2,2-dimethylpropanamide::N-[5-[2-[(5-chloranyl-2-methoxy-phenyl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethyl-propanamide::SMR000156108::cid_11958611

SMILES COc1ccc(Cl)cc1Nc1nc(cs1)-c1sc(NC(=O)C(C)(C)C)nc1C

InChI Key InChIKey=XERLNCVIGMCAMO-UHFFFAOYSA-N

Data  2 IC50  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 100205   

TargetCOUP transcription factor 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM100205(cid_11958611 | N-[5-[2-(5-chloro-2-methoxyanilino)...)
Affinity DataIC50: 1.12E+4nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetTegument protein VP16(HHV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM100205(cid_11958611 | N-[5-[2-(5-chloro-2-methoxyanilino)...)
Affinity DataIC50: 8.54E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCystic fibrosis transmembrane conductance regulator(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM100205(cid_11958611 | N-[5-[2-(5-chloro-2-methoxyanilino)...)
Affinity DataEC50:  870nMAssay Description:Activity of human CFTR F508 deletion mutant expressed in FRT cells assessed as potentiation of genistein-induced iodine ion influx after 24 hrs by YF...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM100205(cid_11958611 | N-[5-[2-(5-chloro-2-methoxyanilino)...)
Affinity DataEC50:  708nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM100205(cid_11958611 | N-[5-[2-(5-chloro-2-methoxyanilino)...)
Affinity DataEC50:  700nMAssay Description:Binding affinity to human CFTR F508 deletion mutant expressed in FRT cells assessed as increase in iodine influx after 16 to 20 hrs by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM100205(cid_11958611 | N-[5-[2-(5-chloro-2-methoxyanilino)...)
Affinity DataKd:  700nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed