BDBM50450369 SIALYL LEWIS X::Sialyl LeX::Sialyl lewis-x::sLex::sialyl LewisX
SMILES [H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]([C@H](O)CO)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](NC(C)=O)C=O)[C@@H]1O)C(O)=O)[C@H](O)[C@H](O)CO
InChI Key InChIKey=LAQPKDLYOBZWBT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 40 hits for monomerid = 50450369
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Selectin P bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against blocking of Selectin P during migration of inflammatory cells to inflammatory siteMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against human chimeric Selectin P-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against human chimeric L-selectin-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibitory activity against human chimeric E-selectin-IgMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Blocking activity using seletin-IgG chimeras in a Selectin P competitive binding assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Blocking activity using seletin-IgG chimeras in a Selectin L competitive binding assay.More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+5nMAssay Description:In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Selectin L bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+5nMAssay Description:Displacement of sialyl Lewis X (sLex) from selectin EMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibitory concentration against blocking of E-selectin during migration of inflammatory cells to inflammatory siteMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+6nMAssay Description:Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin L-IgG fusion proteinsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+6nMAssay Description:Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin E-IgG fusion proteins by 50%.More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+6nMAssay Description:Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin P-IgG fusion proteinsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against Selectin EMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Ability to inhibit the binding to Selectin E immobilized on SPA beads of radiolabeled HL-60 cell membrane was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin E and HL-60 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin E and HL-60 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin P and HL-60 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin P and HL-60 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was tested for its ability to inhibit the binding to recombinant human Selectin E immobilized on SPA beads of radiolabeled HL60 cell membran...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+5nMAssay Description:In vitro inhibitory activity of compound was determined against Selectin E binding by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibitory activity of compound was determined against Selectin P binding by ELISA assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+6nMAssay Description:Ability to inhibit the binding to Selectin E immobilized on SPA beads of radiolabeled HL-60 cell membrane was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+6nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in Selectin EMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+6nMAssay Description:Tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay A) in P-selectinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+6nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in Selectin EMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+6nMAssay Description:Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in P-selectin; value ranges from 1.3-2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for the Selectin E binding activity.More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Ability to inhibit sialyl Lewis X binding to Selectin E was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibitory activity of compound was determined against Selectin L binding by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+6nMAssay Description:Compound was tested for its ability to inhibit sialyl Lewis X dependent binding of HL-60 cells to Selectin E fusion proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibitory activity against binding of Selectin E to human recombinant AGP (alpha-1 acid glycoprotein) containing sLex derivativeMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin E and HL-60 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+6nMAssay Description:Concentration required to inhibit the interaction of Selectin P and HL-60 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibitory concentration against E-selectinMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+6nMAssay Description:In vitro inhibition of HL60 (human leukemia) cell binding to human recombinant e-selectin.More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+6nMAssay Description:In vitro inhibitory activity against sialyl Lewis X expressing HL60 cell binding Selectin LMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+6nMAssay Description:In vitro inhibitory activity against sialyl Lewis X expressing HL60 cell binding Selectin PMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against blocking of Selectin L during migration of inflammatory cells to inflammatory siteMore data for this Ligand-Target Pair