BDBM50338974 2-(3,4-Dimethoxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one::2-(3,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one::5-hydroxy-3,7,3,4-tetramethoxyflavone::CHEMBL77966::NSC-61837::quercetin tetramethyl ether::quercitin-3,7,3',4'-tetramethyl ether::retusin
SMILES COc1cc(O)c2c(c1)oc(-c1ccc(OC)c(OC)c1)c(OC)c2=O
InChI Key InChIKey=HHGPYJLEJGNWJA-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50338974
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MRP1 expressed in human 2008 cells assessed as calcein AM accumulation by cell based assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of MDR1 expressed in MDCK cells using rhodamine 123 staining by flow cytometryMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition me...More data for this Ligand-Target Pair