BDBM50064800 2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethyl-pyridin-2-ylazo)-benzene-1,4-disulfonic acid::CHEMBL69727::isoPPADS::pyridoxal-alpha5-phosphate-6-azophenyl-2',5'-disulfonic acid

SMILES Cc1nc(N=Nc2cc(ccc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O

InChI Key InChIKey=XYBQYEJAMIDMPT-UHFFFAOYSA-N

Data  11 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50064800   

TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 8.35E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X3 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 4.25E+4nMAssay Description:Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X1 receptor expressed in Xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 398nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Wild turkey)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of 10 nM 2-MeS-ADP-stimulated phospholipase C in turkey erythrocyte membranes using [3H]inositolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 43nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 74nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataEC50:  43nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 1 (P2X1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 2(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 400nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 2 (P2X2) receptor 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 84nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 3 (P2X3 )More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 108nMAssay Description:Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 96nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetP2X purinoceptor 1(Mouse)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed