BDBM225876 Polyhydroxy benzophenone, 12::hsp90_175

SMILES c1cc(cc(c1)O)C(=O)c2ccc(cc2O)O

InChI Key InChIKey=NBKYIYGREQXQJY-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 225876   

TargetHeat shock protein HSP 90-beta(Human)
D3R/Abbott

LigandPNGBDBM225876(hsp90_175 | Polyhydroxy benzophenone, 12)
Affinity DataIC50: 8.68E+3nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R
PDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-beta(Human)
D3R/Abbott

LigandPNGBDBM225876(hsp90_175 | Polyhydroxy benzophenone, 12)
Affinity DataKd:  2.89E+4nMAssay Description:Thermofluor AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R
PDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-beta(Human)
D3R/Abbott

LigandPNGBDBM225876(hsp90_175 | Polyhydroxy benzophenone, 12)
Affinity DataKd:  1.15E+4nMAssay Description:ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R
PDB3D3D Structure (crystal)
TargetPolyphenol oxidase 1(White button mushroom)
Sun Yat-Sen University

LigandPNGBDBM225876(hsp90_175 | Polyhydroxy benzophenone, 12)
Affinity DataIC50: 2.00E+5nMpH: 6.8 T: 2°CAssay Description:In brief, a 10 μL sample was added to an assay mixture containing with 10 μL tyrosinase solution (0.5 mg/mL) and 900 μL phosphate buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed