BDBM69609 (2S)-7-hydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one::(2S)-7-hydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8-(3-methylbut-2-enyl)-3,4-dihydro-2H-1-benzopyran-4-one::(2S)-7-hydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8-(3-methylbut-2-enyl)chroman-4-one::(2S)-8-(3-methylbut-2-enyl)-2-[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]-7-oxidanyl-2,3-dihydrochromen-4-one::MLS000697605::SMR000470942::cid_11596309::glabrol

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(ccc1-[#8])-[#6@@H]-1-[#6]-[#6](=O)-c2ccc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2-[#8]-1

InChI Key InChIKey=SAXBGANSQIEGOH-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 69609   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataEC50:  5.84E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Influenza A virus J/8178/09 neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataIC50: 510nMAssay Description:Inhibition of Influenza A virus (A/Puerto Rico/8/1934(H1N1)) neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of Influenza A virus (A/Hong Kong/1/1968(H3N2)) neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM69609(MLS000697605 | (2S)-7-hydroxy-2-[4-hydroxy-3-(3-me...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of oseltamivir-resistant Influenza A virus H1N1 B/55/08 neuraminidase by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed