BDBM50206442 2,6,7-trihydroxy-9-phenyl-3H-xanthen-3-one::CHEMBL375328::cid_70420

SMILES Oc1cc2oc3cc(=O)c(O)cc3c(-c3ccccc3)c2cc1O

InChI Key InChIKey=YDCFOUBAMGLLKA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206442   

TargetMothers against decapentaplegic homolog 3(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50206442(cid_70420 | CHEMBL375328 | 2,6,7-trihydroxy-9-phen...)
Affinity DataIC50: 1.25E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: F.M. Hoffmann, University ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetdTDP-4-dehydrorhamnose reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of California

Curated by ChEMBL
LigandPNGBDBM50206442(cid_70420 | CHEMBL375328 | 2,6,7-trihydroxy-9-phen...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlD assessed as inhibition of dTDP-beta-6-deoxy-L-lyxo-4-hexulose to dTDP-beta-L-rhamnose conversionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50206442(cid_70420 | CHEMBL375328 | 2,6,7-trihydroxy-9-phen...)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of human recombinant GST-PRMT1 expressed in BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetRmtA(Emericella nidulans)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50206442(cid_70420 | CHEMBL375328 | 2,6,7-trihydroxy-9-phen...)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of Aspergillus nidulans recombinant GST-RmtA expressed in BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed