BDBM50007082 (E)-2-methoxy-4-(2-nitrovinyl)phenol::2-Methoxy-4-(2-nitro-vinyl)-phenol::2-methoxy-4-(2-nitrovinyl)phenol::CHEMBL309016::cid_638439

SMILES COc1cc(\C=C\[N+]([O-])=O)ccc1O

InChI Key InChIKey=XVXCSPJSXIUNQJ-UHFFFAOYSA-N

Data  11 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50007082   

TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 4.60E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 1.11E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
Target60S ribosomal protein L19-A(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataEC50:  3.21E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataEC50:  8.18E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetEndothelial PAS domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 1.10E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 4.98E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 4.84E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetTyrosine-protein kinase SYK(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of the epidermal growth factor receptor expressed in A431 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50007082(cid_638439 | 2-Methoxy-4-(2-nitro-vinyl)-phenol | ...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed