BDBM39340 4-Amino-N-(pyrimidin-2-yl) benzenesulfonamide (Sulfadiazine) (14)::MLS000069725::SMR000058213::SULFAPYRIDINE::cid_5336

SMILES Nc1ccc(cc1)S(=O)(=O)Nc1ccccn1

InChI Key InChIKey=GECHUMIMRBOMGK-UHFFFAOYSA-N

Data  4 KI  6 IC50

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 39340   

TargetGenome polyprotein(WNV)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 5.00E+4nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 2.84E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 276nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 1.55E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of PAD4 by ABPP-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataKi:  348nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataKi:  1.17E+4nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataKi:  2.62E+4nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Bovine)
Ondokuz Mayis University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataKi:  9.32E+4nMpH: 7.4Assay Description:The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed