BDBM50303390 3-(3-chlorobenzo[b]thiophen-2-yl)-2-(1-methyl-1H-benzo[d]imidazol-2-yl)-3-oxopropanenitrile::CHEMBL567529::cid_2998581

SMILES Cn1c(nc2ccccc12)C(C#N)C(=O)c1sc2ccccc2c1Cl

InChI Key InChIKey=NWOAKOHSNMYZJJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303390   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50303390(cid_2998581 | CHEMBL567529 | 3-(3-chlorobenzo[b]th...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303390(cid_2998581 | CHEMBL567529 | 3-(3-chlorobenzo[b]th...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain by Flexstation microplate spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303390(cid_2998581 | CHEMBL567529 | 3-(3-chlorobenzo[b]th...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain by quantitative high throughput screeningMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed