BDBM50085551 1,8-Dihydroxy-3-hydroxymethyl-anthraquinone::1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione::CHEMBL40275::aloe emodin::aloe-emodin::cid_10207

SMILES OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1

InChI Key InChIKey=YDQWDHRMZQUTBA-UHFFFAOYSA-N

Data  2 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50085551   

TargetIntestinal-type alkaline phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetAlkaline phosphatase, germ cell type(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetIntestinal-type alkaline phosphatase 1(Rat)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 2.88E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 6.79E+4nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde measured during 1 hr by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat cytosolic aldehyde dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetThioredoxin reductase 1, cytoplasmic(Rat)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase 2, mitochondrial(Rat)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of recombinant SARS coronavirus 3C-like protease trans-cleavage activity by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetP2Y purinoceptor 12(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PSB0413 from human platelet P2Y12 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50085551(cid_10207 | CHEMBL40275 | 1,8-Dihydroxy-3-hydroxym...)
Affinity DataKi:  5.22E+4nMAssay Description:Non-competitive inhibition of sEH (unknown origin) using PHOME as substrate assessed as formation of 6-methoxy-2-naphthaldehyde measured during 30 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed