BDBM50240785 (E)-1-Allyldisulfanyl-3-(prop-2-ene-1-sulfinyl)-propene::(E)-1-allyl-2-(3-(allylsulfinyl)prop-1-enyl)disulfane::CHEMBL122890::ajoene

SMILES C=CCSS\C=C\CS(=O)CC=C

InChI Key InChIKey=IXELFRRANAOWSF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240785   

TargetProstaglandin G/H synthase 2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240785(ajoene | (E)-1-Allyldisulfanyl-3-(prop-2-ene-1-sul...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHTH-type quorum-sensing regulator RhlR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50240785(ajoene | (E)-1-Allyldisulfanyl-3-(prop-2-ene-1-sul...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of quorum sensing regulator protein RhlR in Pseudomonas aeruginosa PAO1 harboring reporter plasmid rhlA-gfp assessed as reduction in rhlA ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHTH-type quorum-sensing regulator RhlR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50240785(ajoene | (E)-1-Allyldisulfanyl-3-(prop-2-ene-1-sul...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of RhlR in Pseudomonas aeruginosa reporter strain harboring gfp-rhlAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50240785(ajoene | (E)-1-Allyldisulfanyl-3-(prop-2-ene-1-sul...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa reporter strain harboring gfp-lasBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed