BDBM50461289 MK-6721::NMED-160::NP-118809::Z-160::Z160

SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=VCPMZDWBEWTGNW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50461289   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461289(Z160 | MK-6721 | NMED-160 | NP-118809 | Z-160)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50461289(Z160 | MK-6721 | NMED-160 | NP-118809 | Z-160)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50461289(Z160 | MK-6721 | NMED-160 | NP-118809 | Z-160)
Affinity DataIC50: 110nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50461289(Z160 | MK-6721 | NMED-160 | NP-118809 | Z-160)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of L type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells in presence of -100 mV holding potential by whole-cel...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit beta-1(Human)
Neuromed Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50461289(Z160 | MK-6721 | NMED-160 | NP-118809 | Z-160)
Affinity DataIC50: 110nMAssay Description:Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed