BDBM50095155 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL316446::ENDOMORPHIN-1::H-Tyr-Pro-Trp-Phe-NH2::Tyr-Pro-Trp-Phe-NH2::YPWF-NH2::endomorphin -1

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=ZEXLJFNSKAHNFH-UHFFFAOYSA-N

Data  49 KI  22 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 80 hits for monomerid = 50095155   

TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 30nMAssay Description:Agonist activity at delta opioid receptor in Kunming mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 4.03nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig intestine assessed as inhibition of electrically evoked myenteric plexus longitudinal mu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 17nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 26nMAssay Description:Agonist activity at delta opioid receptor by inhibition of electrically evoked muscle contraction in isolated mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  0.00100nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 14nMAssay Description:Agonist activity at mu opioid receptor in human SHSY5Y cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  104nMAssay Description:Activity at mu opioid receptor in Wistar rat brain assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 283nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked muscle contractionsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) transfected in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 0.430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  166nMAssay Description:Agonist activity at mu opioid receptor in rat brain membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 1.71E+6nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deference assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 2.80E+4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mu opioid receptor in guinea pig ileum/longitudinal muscle with myenteric plexus assessed as inhibition of electrically-stimulated musc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 65nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 56nMAssay Description:Concentration required for inhibition of [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  932nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human MOP assessed as forskolin stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in human HEK293 cells assessed as increase in cAMP accumulation using [3H]-cAMP as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 14nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 26nMAssay Description:Inhibition of delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 3.20nMAssay Description:Agonist activity at MOP receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 3.58E+3nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 10.1nMAssay Description:Inhibition of Opioid receptor mu 1 of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 36.3nMAssay Description:Inhibition of Mu opioid receptor of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataIC50: 1.89nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity towards Opioid receptor mu 1 by displacing [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]DAMGO from rat cortical MOR by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]DAMGO from MOP receptor expressed in CHO-K1 cells after overnight incubation by beta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  1.11nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  1.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  1.62nMAssay Description:Displacement of [3H]endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]endomorphin-2 from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DAMGO from human cloned mu-opioid receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]DAMGO from rat cortex mu opioid receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  4.21nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes preincubated for 1 hr measured after 1hr by scintillation counting m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
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