BDBM50557738 Wp 1066::Wp1066

SMILES C[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1

InChI Key InChIKey=VFUAJMPDXIRPKO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557738   

TargetSignal transducer and activator of transcription 3(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557738(Wp 1066 | Wp1066)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of IL-6 induced STAT3 transcriptional activity in human HEK-Blue IL-6 cells assessed as secreted embryonic alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557738(Wp 1066 | Wp1066)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of IL-6 induced STAT3 transcriptional activity in human HEK-Blue IL-6 cells assessed as secreted embryonic alkaline phosphatase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557738(Wp 1066 | Wp1066)
Affinity DataIC50: 6.44E+3nMAssay Description:Inhibition of STAT3 in human HEK293 cells assessed as inhibition of IL-6 stimulated STAT3 phosphorylation incubated for 24 hrs by dual-luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed