BDBM50437693 VIALININ A

SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1

InChI Key InChIKey=NOJUKCRPSUMHQQ-UHFFFAOYSA-N

Data  4 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50437693   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human UCH-L1 using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 4(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 5(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSentrin-specific protease 1(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSentrin-specific protease 1(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSentrin-specific protease 1(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human SENP1 catalytic domain assessed as reduction in deSUMOylation of RanGAP1-SUMO2 using RanGAP1-SUMO2 as substrate by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human full-length recombinant SENP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataKi:  930nMAssay Description:Binding affinity to recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSentrin-specific protease 1(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataKi:  1.07E+3nMAssay Description:Binding affinity to full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 5(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 5(Human)
Tokyo University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50437693(VIALININ A)
Affinity DataKi:  1.25E+4nMAssay Description:Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed