BDBM50628032 CHEMBL5418636::US20250026762, Compound 15

SMILES Fc1ccc(cc1)-c1nn(C(=O)N2CCN3CCC2CC3)c2CC3CC3c12

InChI Key InChIKey=PXSSHCJWSPTXFH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628032   

TargetCeramide glucosyltransferase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50628032(CHEMBL5418636 | US20250026762, Compound 15)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of GCS in human A-375 cell golgi body using C6-ceramide and UDP-glucose as substrate assessed as reduction in UDP production preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50628032(CHEMBL5418636 | US20250026762, Compound 15)
Affinity DataEC50:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2025
Entry Details
Go to US Patent