BDBM50431239 CHEMBL2333029

SMILES C[C@@H](NC(=O)c1ccncc1F)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=ODUXGFPXUMBHHE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431239   

TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431239(CHEMBL2333029)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431239(CHEMBL2333029)
Affinity DataIC50: 15nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431239(CHEMBL2333029)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts University Sackler School of Biomedical Sciences

Curated by ChEMBL
LigandPNGBDBM50431239(CHEMBL2333029)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM50431239(CHEMBL2333029)
Affinity DataIC50: 1.34E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM50431239(CHEMBL2333029)
Affinity DataIC50: 1.57E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent