BDBM565443 US11414431, Compound I-9::US12221453, Compound I-9

SMILES CNc1cc(Nc2cccn([C@@H]3C[C@@H](C3)OC)c2=O)nc2c(cnn12)C(=O)N[C@@H]1C[C@@H]1F

InChI Key InChIKey=XBUSIKNNSDRTCC-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 565443   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM565443(US11414431, Compound I-9 | US12221453, Compound I-...)
Affinity DataKd: <0.200nMAssay Description:The binding reaction was assembled by combining 16 μl of DNA-tagged kinase extract, 3.8 μl liganded affinity beads, and 0.18 μl test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM565443(US11414431, Compound I-9 | US12221453, Compound I-...)
Affinity DataKd:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent