BDBM424699 US10508120, Compound I-1203::US10577373, Compound I-1203::US11046698, Compound I-1203::US11414431, Compound I-42
SMILES CNc1cc(Nc2cccn([C@@H]3C[C@H]3F)c2=O)nc2c(cnn12)C(=O)N[C@@H]1CC[C@H](O)C1
InChI Key InChIKey=FVVAPARGJLGJEV-UHFFFAOYSA-N
Data 5 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 424699
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
Affinity DataKd: 0.600nMAssay Description:The binding reaction was assembled by combining 16 μl of DNA-tagged kinase extract, 3.8 μl liganded affinity beads, and 0.18 μl test c...More data for this Ligand-Target Pair