BDBM620408 US11767305, Compound S-5-MAPB

SMILES CN[C@@H](C)Cc1ccc2occc2c1

InChI Key InChIKey=ZOVRTIPCNFERHY-UHFFFAOYSA-N

Data  1 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 620408   

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB)
Affinity DataIC50: 60.4nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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Target5-hydroxytryptamine receptor 1B(Rat)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB)
Affinity DataEC50:  161nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB)
Affinity DataIC50: 60.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent